Noxilizer Inc
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Manufacturing
Decontamination and depyrogenation in aseptic filling operations
Sterilisation equipment developer Noxilizer and aseptic liquid processing technology provider Weiler Engineering have worked together to put the ‘c’ in cGMP through improvements in decontamination and deypyrogenation process technology
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Containment
Isolator decontamination with nitrogen dioxide
The majority of isolators are decontaminated using hydrogen peroxide vapour technologies, but limitations in process control, aeration efficiency, and product compatibility have led to research into new decontamination methods. DNA in mammalian cells is degraded via single-strand breaks upon exposure to nitrogen dioxide, which is now being developed as a sterilant.