US-based BNBuilders completes BSL-3 lab remodel in California

The project for the University of California's Riverside School of Medicine offered Biosafety Level 3 containment of dangerous biological agents

BSL-3 Laboratory at UC Riverside School of Medicine, built by BNBuilders:
Picture courtesy of BNBuilders

This US$2 million project involved converting an existing laboratory space into a BSL-3 suite for faculty research programmes.†An experienced builder for this type of specialised construction, BNBuilders has completed numerous technologically-advanced life science and research facilities throughout the West Coast of the US.

At UC Riverside's School of Medicine, BNBuilders completed selective demolition of existing laboratory space and infrastructure in an occupied building, and constructed new procedure rooms and research space with new dedicated mechanical systems.

The 1,383 ft2 remodel included an anteroom, gowning/de-gowning room, shower area, procedure rooms, an autoclave, biosafety cabinets, and other specialised equipment.

BNBuilders also ensured that the laboratory met BSL-3 specifications to ensure appropriate containment of dangerous biological agents. BSL-3 laboratories must be behind two sets of self-closing doors, and any seams in the floors, walls, windows, and ceilings must be sealed to prevent any microbes from leaving the suite and for easy cleaning and decontamination.

The ventilation system must force clean air into the lab where infectious agents are handled, and air from inside the laboratory must be filtered before it can be exhausted back into the atmosphere. BSL-3 is commonly assigned to facilities that work with tuberculosis, SARS, yellow fever, and West Nile virus.

Jamie Awford, Principal at BNBuilders, said: "This lab will offer new opportunities for UC Riverside researchers to contribute to the worldwide knowledge of and treatments for dangerous pathogens. We are proud to be a part of that important work."†