AdvanceTEC, the cleanroom design, construction, and mission-critical process integration expert, has completed another integrated project delivery cleanroom project for a leading EPCM innovator and leading cell & gene therapy CDMO in Research Triangle Park, North Carolina. AdvanceTEC utilised LEAN tools to complete the project ahead of schedule and under budget. As a part of this project, AdvanceTEC was responsible for addressing process integration requirements as well as turn-key design-build cleanroom construction requirements for gene therapy, cell therapy, and single-use disposable manufacturing platforms.
AdvanceTEC was selected for this critical project based on the company’s demonstrated ability to successfully execute fast-track projects providing certainty of cost, schedule, and performance. Key to delivering this project was AdvanceTEC’s offsite prefabrication facility. This strategic capability leverages prefabrication, preassembly, modularisation, and offsite fabrication (PPMOF) to reduce risks, increase safety and quality, as well as enhance site logistics and JIT onsite installation.
“AdvanceTEC is honoured once again to work with a pioneer in single-use and gene therapy technologies,” noted Bryan Phelan, AdvanceTEC managing partner, and director of customers. “This was an incredible team effort. It was great to see the members of the team push themselves individually and as a group to hit our original committed dates for turn-over and validation.”
AdvanceTEC Delivers “Total Performance” for Biotech Industry Leading EPCM and CDMO
Drew Fischer, one of AdvanceTEC’s director of operations stated: “The number one key to the project’s success was the overall teamwork that was displayed from start to finish. From our engineering and operations team to our trade partners and client representatives, all parties displayed the can-do attitude that was required to make things happen.”
Fischer continued: “Safety and quality was our top priority. Our focus was to limit impacts to the project by keeping the crews safe and minimising any rework. These types of details are so valuable as it shows that it will directly improve the project schedule and culture.”
AdvanceTEC will be providing turn-over training materials in the upcoming weeks. This 140,000 sqft facility contains clean areas ranging from Controlled Non-Classified to ISO Class 8, ISO Class 7, and ISO 5 spaces. The cleanrooms are outfitted with pharmaceutical-grade doors, liners, and wall panels. AdvanceTEC’s construction team installed a pharmaceutical-grade walkable ceiling with walkable lights integrated in the system. The team also provided custom stainless- steel fabrications for this project.
