Nasal spray study proven to kill MRSA

Published: 17-Oct-2008

A preliminary in vivo pilot study of a nasal spray has shown it to be good at controlling the spread of the MRSA infection.


These favourable results from SinoFresh HealthCare, a developer and marketer of innovative upper respiratory system therapies, follow an earlier, successful in vitro study that was conducted at the Public Health Research Institute – under the direction of Dr Barry Kreiswirth, director of the Tuberculosis Center and Hospital Infections Program.

“The study showed that SinoFresh nasal spray used three times daily appeared to effectively eliminate MRSA in the noses of the test animals while leaving enough normal microbes to keep a normal population in the nasal passages," said Dr John Todhunter, consultant to SinoFresh, who oversaw the study conducted at Virion Systems in Rockville, MD.

SinoFresh nasal spray attacks MRSA in the nasal passages by destroying the "super-bugs" cell walls and membranes by physical means rather than by an antibiotic mechanism involving attack on the metabolism of the microbes as occurs with the use of antibiotics. "Since bacteria can in effect change their metabolism to be resistant to antibiotics, but can't very well change the laws of physics the chances for development of resistance to SinoFresh(R) Nasal Spray's mode of killing them is much lower said Todhunter."

William Wilferth, vice president for research and development at SinoFresh, said: "These results have exceeded our expectations. The positive results of this in vivo study gives us the solid scientific platform we have needed in order to advance our efforts to fight MRSA to the next level."

Charles Fust, ceo of SinoFresh, noted that the data reported is extremely encouraging and that there is a significant market need for new methods to address MRSA control which is believed to be as many as 80 to 100 million treatments annually in the US alone.

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